Glixx Laboratories Inc

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Glixx Laboratorie

 

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MIF098

 

CAS: 1208448-95-6

 

Chemical Name: 3-(3-Hydroxybenzyl)-5-methylbenzo[d]oxazol-2(3H)-one

 

 
GLXC-11317For Lab R&D Uses Only
        Cat No: GLXC-11317

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel antagonist of macrophage migration inhibitory factor (MIF), decreasing RVSP and inhibiting distal pulmonary artery hyperproliferation, muscularization, and collagen deposition in hypoxia challenged mice, inhibiting PASMC proliferation and migration by regulating mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 (MAPK/ERK1/2) signal- and cell-cycle-related proteins, reducing collagen synthesis by inhibiting the TGFβ1/Smad2/Smad3 pathway in cell-based experiments

 

References:

https://pubmed.ncbi.nlm.nih.gov/?term=MIF098&sort=date

 

Analytical data click for PDF file

 

 

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