Glixx Laboratories Inc

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Glixx Laboratorie

 

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T1742 (ML107)

 

CAS: 328998-25-0

 

Chemical Name: 4E1RCat; 4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid

 

GLXC-02289Cat No: GLXC-02289

 

 

Purity:               > 98% (HPLC)

Storage:             Refrigerator (4 °C)

 


Product Description:

Novel inhibitor of eukaryotic translation initiation; Novel cap-dependent translation inhibitor, preventing eIF4F formation, blocking the ATG5-ATG16L1 and ATG5-TECAIR interactions in the in vitro binding assay (IC50 = 1-2 μM) and also exhibiting autophagy inhibition in cellular assays

 

References:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01233

https://pubmed.ncbi.nlm.nih.gov/?term=4E1RCat&sort=date

 

Analytical data click for PDF file

 

 

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