Glixx Laboratories Inc

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Glixx Laboratorie

 

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Ponicidin

 

CAS: 52617-37-5

 

Chemical Name: Rubescensine B; (1R,2S,8R,9S,11S,13S,14S,15R,19S)-13,14,19-trihydroxy-16,16-dimethyl-6-methylidene-10,12-dioxahexacyclo[9.8.0.01,15.02,8.05,9.08,13]nonadecan-7-one

 

 
GLXC-17962For Lab R&D Uses Only
        Cat No: GLXC-17962

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Natural antitumor agent, significantly inhibiting the proliferation and migration of HCC cells, promoting the formation of the Keap1‐PGAM5 complex, leading to the ubiquitination of PGAM5, activating the cysteine‐dependent mitochondrial pathway via PGAM5, resulting in mitochondrial damage and ROS production, thereby promoting mitochondrial apoptosis in HepG2 cells

 

References:

https://pubmed.ncbi.nlm.nih.gov/?term=Ponicidin&sort=date


Analytical data click for PDF file

 

 

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