For Lab R&D Uses Only

Purity:               >98% (HPLC)

Product Description:

First-in-class citron kinase (CITK) chemical probe, potently inhibiting CITK catalytic activity (biochemical IC₅₀ = 12 nM), binding directly to full-length human CITK in cells (NanoBRET K_d < 10 nM), and demonstrating favorable DMPK properties for in vivo evaluation

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01807

Analytical data

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