Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2566733-45-5
Chemical Name: 7-Cyclopentyl-2-((4-((6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)carbamoyl)phenyl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
The first-in-class Aurora-A/N-Myc degrader, promoting degradation of Aurora-A and N-Myc with superior potency and excellent selectivity in comparison to established allosteric Aurora-A inhibitors
References:
https://www.cell.com/cell-chemical-biology/abstract/S2451-9456(24)00516-6
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202400703
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202300649
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