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(S)-ACE-OH

 

CAS: N/A

 

Chemical Name: (S)-Hydroxyl-acepromazine; (S)-1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)ethan-1-ol

 

 
GLXC-29227For Lab R&D Uses Only
        Cat No: GLXC-29227

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Metabolite of acepromazine (ACE), acting as a molecular glue to induce an interaction between the E3 ubiquitin ligase TRIM21 and the nucleoporin NUP98, leading to the degradation of nuclear pore proteins and disruption of nucleocytoplasmic trafficking

 

Reference:

https://www.cell.com/cell/abstract/S0092-8674(24)01197-8

 

Analytical data click for PDF file

 

 

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