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HDAC6 inhibitor 25202

 

CAS: N/A

 

Chemical Name: N-Hydroxy-4-((2-methyl-5-oxoimidazo[1,2-c]quinazolin-6(5H)-yl)methyl)benzamide

 

 
GLXC-29633For Lab R&D Uses Only
        Cat No: GLXC-29633

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent HDAC6 inhibitor (IC50, 3.5 nM), significantly decreasing HDAC6 protein expression, disrupting microtubule organization, also increasing the phosphorylation of CDC20, BUB1, and BUBR1, indicating the activation of the spindle assembly checkpoint (SAC)

 

Reference:

https://onlinelibrary.wiley.com/doi/10.1002/pros.24678


Analytical data click for PDF file

 

 

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