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UH15-38

 

CAS: 2540881-21-6

 

Chemical Name: 3-(3-Hydroxyphenyl)-1-methyl-7-[3-(4-methylpiperazin-1-yl)anilino]-1,6-naphthyridin-2-one

 

 
GLXC-28984For Lab R&D Uses Only
        Cat No: GLXC-28984

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent and selective RIPK3 inhibitor with an IC50 value of 20 nM, selectively blocking IAV-triggered necroptosis in alveolar epithelial cells in vivo, ameliorating lung inflammation and preventing mortality following infection with laboratory-adapted and pandemic strains of IAV, without compromising antiviral adaptive immune responses or impeding viral clearance

 

Reference:

https://www.nature.com/articles/s41586-024-07265-8

 

Analytical data click for PDF file

 

 

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