Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 3029695-07-3
Chemical Name: 2-Butyl-1-((tetrahydrofuran-3-yl)methyl)-1H-imidazo[4,5-c]quinolin-4-amine
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent and specific TLR7 agonist (EC50 = 0.024 ± 0.002 μM), resulting in recruitment of the MyD88 adaptor protein and activation of the NF-κB and MAPK signaling pathways, exerting immune-enhancing effects by significantly inducing the secretion of proinflammatory cytokines in murine dendritic cells, macrophages, and human peripheral blood mononuclear cells while promoting M1 macrophage polarization
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01504
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