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Glixx Laboratorie
CAS: 2896739-91-4
Chemical Name: ((1S,2S)-2',3'-Difluoro-5-(4-methylpent-3-en-1-yl)-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2-yl)(2,6-dihydroxyphenyl)methanone
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel nicolaioidesin C (Nic-C) derivative, exhibiting superior cytotoxicity against MIA PaCa-2 and PANC-1 pancreatic cancer cells, inhibiting MIA PaCa-2 cell migration and colony formation, and modulating the PI3K/Akt/mTOR pathway, while reducing the ER stress markers induced by gemcitabine
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01141
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