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Nic-15

 

CAS: 2896739-91-4

 

Chemical Name: ((1S,2S)-2',3'-Difluoro-5-(4-methylpent-3-en-1-yl)-1,2,3,6-tetrahydro-[1,1'-biphenyl]-2-yl)(2,6-dihydroxyphenyl)methanone

 

 
GLXC-28788For Lab R&D Uses Only
        Cat No: GLXC-28788

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel nicolaioidesin C (Nic-C) derivative, exhibiting superior cytotoxicity against MIA PaCa-2 and PANC-1 pancreatic cancer cells, inhibiting MIA PaCa-2 cell migration and colony formation, and modulating the PI3K/Akt/mTOR pathway, while reducing the ER stress markers induced by gemcitabine

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01141

 

Analytical data click for PDF file

 

 

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