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CAS: 2973373-10-1
Chemical Name: 1-((S)-2-((S)-7-(2,4-Difluoro-6-(2-methoxyethoxy)phenyl)-4-(1-methyl-1H-indazol-5-yl)thieno[3,2-c]pyridin-6-yl)-4-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)prop-2-en-1-one
For Lab R&D Uses Only
Purity: >98% (HPLC)
First-in-class PI3Kα:RAS interaction inhibitor, covalently binding to Cys242 in the RBD of PI3Kα, blocking interactions with all RAS isoforms while preserving PI3Kα kinase function
Reference:
https://www.science.org/doi/10.1126/science.adq2004
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