Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2089314-64-5
Chemical Name: N-[2-[[2-(3-Methoxyphenoxy)phenyl]amino]-2-oxoethyl]-1-naphthalenecarboxamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel PCNA ligand, targeting transcription-replication conflict for selective chemotherapy, enhancing PCNA and RPB1 interaction and interferes with TRC resolution, inducing DNA double-stranded breaks in a transcription dependent manner, suppressing tumor growth but causes no discernable side effect
Reference:
https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00221-0
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