For Lab R&D Uses Only

Purity:               >98% (HPLC)

Product Description:

Novel NIR-II ligand radical, inducing highly immunogenic pyroptosis in tumor cells under both normoxic and severe hypoxic conditions upon 1064 nm laser irradiation, triggering the release of damage-associated molecular patterns (DAMPs) and proinflammatory cytokines, fueling a robust antitumor immune response, significantly inhibiting 4T1 tumor growth in BALB/c mice with a high inhibitory rate of 85.7%

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c02260

Analytical data

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