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LDD_39

 

CAS: 3028786-01-5

 

Chemical Name: Ligand-directed degrader 39; N-(1-(5-(3-Cyano-6-ethoxypyrazolo[1,5-a]pyridin-4-yl)pyridin-2-yl)-4-((4-(3-(4-(2-(2,6-dioxopiperidin-3-yl)-3-oxoisoindolin-5-yl)piperidin-1-yl)cyclobutane-1-carbonyl)piperazin-1-yl)methyl)piperidin-4-yl)-2,5-difluorobenzamide

 

 
GLXC-29424For Lab R&D Uses Only
        Cat No: GLXC-29424

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel heterobifunctional degrader of rearranged during transfection (RET) kinase, demonstrating high in vitro inhibitory and degradation potency against both RET wild-type and the two representative mutants, V804M and G810R

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c02083

 

Analytical data click for PDF file

 

 

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