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CAS: N/A
Chemical Name: N-(5-Fluoro-2-(4-(sulfamoylamino)piperidin-1-yl)phenyl)-8-(2-fluoro-6-methoxyphenyl)imidazo[1,2-a]pyrazine-6-carboxamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel highly potent and selective ENPP1 inhibitor (IC50 value of 5.70 or 9.68 nM), enhancing the mRNA expression of cGAMP-induced STING pathway downstream target genes, such as IFNB1, CXCL10, and IL6
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01634
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