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Glixx Laboratorie
CAS: N/A
Chemical Name: 4-(4-Methoxy-1H-pyrrolo[2,3-b]pyridine-3-yl)pyridine-2,6-diamine
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel pan CDK inhibitor, prevalently inhibiting most of the CDKs (such as CDK1, 2, 3, 5, 7, 8, 9, 12, 13, 16, 17, 18, 19, 20), preventing the CDK9-mediated phosphorylation of RNA polymerase II at Ser2 which is crucial for transcription initiation
Reference:
https://www.nature.com/articles/s41420-024-02056-6
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