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Glixx Laboratorie
CAS: 3056394-59-0
Chemical Name: 1-(4-(4-(2-((4-Chloro-3-(piperazin-1-ylsulfonyl)phenyl)amino)pyrimidin-4-yl)pyridin-2-yl)phenyl)-3-methylurea
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel SMG1 inhibitor, elevating the expression of transcripts and proteins resulting from human and murine truncating mutations, increasing the presentation of immune-targetable human leukocyte antigens (HLA) class I-associated peptides from NMD-downregulated proteins on the surface of human cancer cells
Reference:
https://elifesciences.org/articles/95952
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