Glixx Laboratories Inc

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Glixx Laboratorie

 

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EN171

 

CAS: 2191110-79-7

 

Chemical Name: 1-(7-Benzyl-2,7-diazaspiro[4.4]nonan-2-yl)prop-2-en-1-one

 

 
For Lab R&D Uses Only
        Cat No: GLXC-29235

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel covalent 14-3-3 PPI molecular glue, targeting both C38 and C96 on 14-3-3 to enhance 14-3-3 interactions with ERα, YAP, and TAZ, leading to impaired estrogen receptor and Hippo pathway transcriptional activity

 

References:

https://pubs.acs.org/doi/10.1021/jacs.3c12389

https://www.biorxiv.org/content/10.1101/2023.11.06.565850v1.full

 

Analytical data click for PDF file

 

 

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