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CAS: 1678539-08-6
Chemical Name: 3-[2-(3,5-Dihydroxyphenyl)ethynyl]chromen-4-one
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel AMPK activator, significantly stimulating fatty acid oxidation and the expression of related genes (Sirt1, Pgc1α and Mcad) in C2C12 myotubes, and inhibiting fatty acid synthesis in HepG2 cells, dose-dependently increasing the phosphorylation of AMPK and ACC in both C2C12 myotubes and HepG2 cells
Reference:
https://www.nature.com/articles/aps2014147
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