Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2923208-52-8
Chemical Name: (1H-Benzoimidazol-2-ylmethyl)-(2-morpholin-4-yl-9-thiophen-3-yl-9H-purin-6-yl)-amine
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent Zinc Finger Protein 207 (ZNF207) inhibitor with IC50 values ranging from 0.5-2.5 μM for inhibiting sphere formation and 0.5-15 μM for cytotoxicity, hindering tumorigenesis and migration and promoting apoptosis in vitro, exhibiting efficient permeability across the blood-brain barrier and potent efficacy in both subcutaneous and orthotopic glioma tumor models
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c02241
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