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CAS: N/A
Chemical Name: N-(2-((((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)ethyl)-N-(3-bromobenzyl)-3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel prodrug of YD1130, exhibiting potent inhibition on cellular substrate methylation, breast cancer cell colony formation, and tumor growth in the animal model, surpassing or matching known PRMT4-specific inhibitors
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01041
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