Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2604513-53-1
Chemical Name: (R)-9-((5-(3-Amino-3-(pyridin-2-yl)piperidin-1-yl)-2-(3,4-difluorophenyl)pyridin-4-yl)methyl)-9H-purin-6-amine
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel highly potent and selective inhibitor of NSD2 (IC50 of 8.8 nM, >300-fold selective over a KMT panel including NSD1, NSD3 and SETD2), showing broad therapeutic efficacy in KRAS-driven preclinical cancer models
Reference:
https://www.nature.com/articles/s41586-025-09299-y
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