Glixx Laboratories Inc

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IACS-17596

 

CAS: 2604513-53-1

 

Chemical Name: (R)-9-((5-(3-Amino-3-(pyridin-2-yl)piperidin-1-yl)-2-(3,4-difluorophenyl)pyridin-4-yl)methyl)-9H-purin-6-amine

 

 
GLXC-29587For Lab R&D Uses Only
        Cat No: GLXC-29587

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel highly potent and selective inhibitor of NSD2 (IC50 of 8.8 nM, >300-fold selective over a KMT panel including NSD1, NSD3 and SETD2), showing broad therapeutic efficacy in KRAS-driven preclinical cancer models

 

Reference:

https://www.nature.com/articles/s41586-025-09299-y

 

Analytical data click for PDF file

 

 

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