Glixx Laboratories Inc

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MS28

 

CAS: 2229974-73-4

 

Chemical Name: (2S,4R)-1-((S)-2-(7-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-7-oxoheptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

 

 
GLXC-28872For Lab R&D Uses Only
        Cat No: GLXC-28872

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

The first-in-class degrader of cyclin D1, showing superior degradation efficiency than CDK4/6, through recruiting the CDK4/6-cyclin D1 complex to the von Hippel-Lindau E3 ligase, suppressing the proliferation of cancer cells more effectively than CDK4/6 inhibitors and degraders

 

Reference:

https://pubs.acs.org/doi/10.1021/jacs.2c09255

 

Analytical data click for PDF file

 

 

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