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NLRP3 inhibitor P33

 

CAS: 3040298-34-5

 

Chemical Name: (S)-5-(4-((1-(2-Hydroxyethyl)piperidin-3-yl)amino)-5,6,7,8-tetrahydro-5,8-ethanophthalazin-1-yl)benzofuran-4-ol

 

 
GLXC-28863For Lab R&D Uses Only
        Cat No: GLXC-28863

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent, specific, and orally available NLRP3 inflammasome inhibitor, exhibiting significant inhibitory effects against nigericin-induced IL-1β release in THP-1 cells, BMDMs, and PBMCs, with IC50 values of 2.7, 15.3, and 2.9 nM, respectively

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01341


Analytical data click for PDF file

 

 

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