Glixx Laboratories Inc

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Glixx Laboratorie

 

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SPP10

 

CAS: 2758436-98-3

 

Chemical Name: 1',4'-Diphenyl-7'-(thiophen-3-yl)spiro[cyclohexane-1,5'-pyrrolo[3,4-d]pyridazine]

 

 
GLXC-28661For Lab R&D Uses Only
        Cat No: GLXC-28661

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel anticancer agent, potently inducing apoptotic cell death in MCF-7, H69AR, and PC-3 cancer cells, demonstrating selective cytotoxicity against cancer cells with a low impact on nontumorigenic cells (IC50 value: 26.8 ± 0.4 μM), inhibiting antiapoptotic Bcl-2 while inducing pro-apoptotic Bax and cytochrome c, exhibiting significant EGFR kinase inhibitory activity

 

Reference:

https://pubs.acs.org/doi/10.1021/acsomega.4c00794


Analytical data click for PDF file

 

 

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