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CAS: N/A
Chemical Name: N-(2-(2-(((3-(3-Carbamothioylphenyl)-7-chloro-1-(tetrahydro-2H-pyran-4-yl)-1H-indol-6-yl)methyl)carbamoyl)-7-azaspiro[3.5]nonan-7-yl)ethyl)thiazole-2-carboxamide hydrochloride
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel highly potent and selective ASH1L inhibitor (IC50 = 94 nM), effectively blocking cell proliferation and inducing apoptosis and differentiation in leukemia cells harboring MLL1 translocations
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01673
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