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CZH-726

 

CAS: N/A

 

Chemical Name: HDAC8 PROTAC Z16; 2-(4-(4-((2,6-Dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)-N-(4-(2-hexylhydrazine-1-carbonyl)benzyl)acetamide

 

 
GLXC-28815For Lab R&D Uses Only
        Cat No: GLXC-28815

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent and selective HDAC8 PROTAC with low nanomolar DC50 values in various cell lines, inducing structural maintenance of chromosomes protein 3 (SMC3) hyperacetylation at low concentrations and histone hyperacetylation at high concentrations

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00836

 

Analytical data click for PDF file

 

 

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