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CAS: N/A
Chemical Name: HDAC8 PROTAC Z16; 2-(4-(4-((2,6-Dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)-N-(4-(2-hexylhydrazine-1-carbonyl)benzyl)acetamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent and selective HDAC8 PROTAC with low nanomolar DC50 values in various cell lines, inducing structural maintenance of chromosomes protein 3 (SMC3) hyperacetylation at low concentrations and histone hyperacetylation at high concentrations
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00836
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