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Glixx Laboratorie
CAS: 300815-04-7
Chemical Name: [2,2,2-trichloro-1-(2-pyrimidinylamino)ethyl]-carbamic acid 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl ester
Cat No: GLXC-05330
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Novel inhibitor of the anaphase-promoting complex/cyclosome (APC/C), blocking mitotic exit and being synergistically amplified by co-addition of Ts-Arg-OMe (GLXC-05331)
References:
1) https://onlinelibrary.wiley.com/doi/full/10.1002/cbf.3550
2) https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b02097
3) https://www.nature.com/articles/s41589-020-0495-z
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