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CAS: N/A
Chemical Name: (11R,16S)-1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-16-(4-(((2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzamido)-11-carboxy-2,2-dimethyl-4,13-dioxo-3,5-dioxa-8,9-dithia-12-azaheptadecan-17-oic acid
Purity: >98% (HPLC)
Novel folate-targeted TLR7 agonist, selectively accumulating in profibrotic macrophages and suppressing fibrosis-inducing cytokine production, reprograming M2-like fibrosis-inducing macrophages into fibrosis-suppressing macrophages, resulting in dramatic declines in profibrotic cytokine release, hydroxyproline biosynthesis, and collagen deposition, with concomitant increases in alveolar airspaces
Ref: https://www.embopress.org/doi/full/10.15252/emmm.202012034
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