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PD-L1 degrader P22

 

CAS: 2447066-37-5

 

Chemical Name: 5-(4-(1-(5-Chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)benzyl)piperidine-2-carbonyl)piperazin-1-yl)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-5-oxopentanamide

 

 
GLXC-24270For Lab R&D Uses Only
        Cat No: GLXC-24270

 

Purity:               >95% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel PROTAC dual inhibitor and degrader of PD-L1, inhibiting PD-1/PD-L1 interaction with IC50 of 39.2 nM in an HTRF binding assay

 

Ref: https://www.sciencedirect.com/science/article/pii/S0223523420303470

 

Analytical data click for PDF file

 

 

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