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CAS: 2756566-45-5
Chemical Name: 4-(4-((4,4-Dimethylpiperidin-1-yl)methyl)-2,5-difluorophenyl)-9-(6-(methylamino)pyrimidin-4-yl)-1,4,9-triazaspiro[5.5]undecan-2-one
Purity: >98% (HPLC)
Novel potent and selective METTL3 inhibitor (IC50 of 5 nM), reducing the m6A/A level of polyadenylated RNA in MOLM-13 (acute myeloid leukemia) and PC-3 (prostate cancer) cell lines
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00773
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