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JAK/HDAC inhibitor 30

 

CAS: N/A

 

Chemical Name: 7-(4-((4-((3-(N-(tert-Butyl)sulfamoyl)phenyl)amino)-5-methylpyrimidin-2-yl)amino)-2-fluorophenoxy)-N-hydroxyheptanamide

 

 
GLXC-27246For Lab R&D Uses Only
        Cat No: GLXC-27246

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel dual JAK/HDAC inhibitor, potently inhibiting HDAC3/6 and JAK1/2 at nanomolar levels and exhibiting splendid selectivity for the JAK2 against a panel of 76 kinases, presenting remarkable antiproliferative activity in both hematological malignancies and solid cancers

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00036


Analytical data click for PDF file

 

 

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