Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1942114-09-1
Chemical Name: 2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
Cat No: GLXC-09553
For Lab R&D Uses Only
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Novel allosteric inhibitor of selected drug-resistant EGFR mutants, overcoming EGFR(T790M) and EGFR(C797S) resistance
References:
1) https://www.tandfonline.com/doi/abs/10.1080/07391102.2020.1734092
2) https://www.sciencedirect.com/science/article/abs/pii/S0304383516306863
3) https://www.nature.com/articles/nature17960
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