Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 1-(4-((7-Fluoroquinazolin-4-yl)oxy)phenyl)-3-phenylurea
Purity: >98% (HPLC)
Novel orally active and selective CSF1R inhibitor (IC50 = 0.53 nM), specifically inhibited protumor M2-like macrophage survival with a minimal effect on antitumor M1-like macrophage growth, exhibiting antitumor and immunomodulatory activity in a murine colon tumor model
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01006
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