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NLRP3 Inhibitor 4b

 

CAS: N/A

 

Chemical Name: Sodium ((3,5-dimethylphenyl)carbamoyl)((4-(2-hydroxypropan-2-yl)furan-2-yl)sulfonyl)amide

 

 
GLXC-25574For Lab R&D Uses Only
        Cat No: GLXC-25574

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel NLRP3 inhibitor, reducing caspase-1 activation, oligomerization of ASC, and therefore, IL-1β processing, showing a significant anti-inflammatory effect and reduced mechanical hyperalgesia at 3 and 10 mg/kg (i.p.) in an in vivo mouse of gout

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00149

 

Analytical data click for PDF file

 

 

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