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Glixx Laboratorie
CAS: N/A
Chemical Name: Sodium ((3,5-dimethylphenyl)carbamoyl)((4-(2-hydroxypropan-2-yl)furan-2-yl)sulfonyl)amide
Purity: >98% (HPLC)
Novel NLRP3 inhibitor, reducing caspase-1 activation, oligomerization of ASC, and therefore, IL-1β processing, showing a significant anti-inflammatory effect and reduced mechanical hyperalgesia at 3 and 10 mg/kg (i.p.) in an in vivo mouse of gout
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00149
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