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CAS: N/A
Chemical Name: (S)-16-(4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzamido)-1-(4-(((5S,8S)-8-benzyl-1-((4-((((S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl)oxy)methyl)phenyl)amino)-5-isobutyl-1,4,7,10,13-pentaoxo-15,18,21-trioxa-3,6,9,12-tetraazatricosan-23-yl)oxy)-1H-1,2,3-triazol-1-yl)-13-oxo-3,6,9-trioxa-12-azaheptadecan-17-oic acid
Purity: >98% (HPLC)
Novel Folate Receptor Targeting and Cathepsin B-Sensitive Drug Delivery System for Selective Cancer Cell Death and Imaging, exhibited strong cytotoxicity against FR-overexpressing SK-Hep-1, HeLa, and Siha cells, with IC50 values of 2-3 μM, but had no effect on FR-negative A549 and 16-HBE cells
Ref: https://pubs.acs.org/doi/10.1021/acsmedchemlett.0c00031
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