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CAS: N/A
Chemical Name: Methyl (4S,7S,E)-7-(aminomethyl)-4-(4-hydroxyphenethyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazahexadec-14-en-16-oate
Purity: >98% (HPLC)
Novel covalent inhibitor of the SARS-CoV-2 papain-like protease (PLpro), irreversibly inactivate PLpro by forming a covalent bond with a specific residue of the catalytic site (Cys111), through a Michael addition reaction
References:
1) https://www.mdpi.com/1422-0067/23/10/5855
2) https://pubs.acs.org/doi/10.1021/acs.jpcb.1c07060
3) https://www.biorxiv.org/content/10.1101/2020.04.29.068890v2
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