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Degradomer D-1

 

CAS: N/A

 

Chemical Name: IRAK3 degrader D-1; (2S,4R)-1-((S)-2-((1r,4S)-4-(4-(4-(6-Amino-5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carbonyl)cyclohexane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide

 

 
GLXC-25746For Lab R&D Uses Only
        Cat No: GLXC-25746

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel selective proteasomal degrader of IRAK3, reproducing the 1L-12p40 increases observed in the CRISPR/Cas9 knockout

 

Ref: https://pubs.acs.org/doi/10.1021/acschembio.2c00037

 

Analytical data click for PDF file

 

 

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