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CAS: N/A
Chemical Name: HSP27 inhibitor 32; N-[3-(2,5-Dimethoxybenzyloxy)-4-[methyl(methylsulfonyl)amino]phenyl]-4-methoxybenzamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel inhibitor of heat shock 27 kDa protein (HSP27), significantly inducing AR degradation in GBM cells via the proteasomal pathway, selectively inhibiting AR-overexpressed GBM cell growth with IC50 values around 5 nM
References:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01537
https://pubs.acs.org/doi/10.1021/jm4004736
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