Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: (E)-(1-(Hydroxymethyl)-3-(3-isobutyl-5-methylhexylidene)-2-oxocyclopentyl)methyl pivalate
Purity: >98% (HPLC)
Novel protein kinase C (PKC) activator, preferentially binding to the novel PKC isoforms PKCδ and PKC∈, stimulated a striking preferential redistribution of PKC∈ to the plasma membrane relative to PKCα, inducing major changes in cytoskeletal reorganization in lung cancer cells, as determined by the formation of membrane ruffles, via activation of novel PKCs
References:
1) https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00739
2) https://www.jbc.org/article/S0021-9258(20)39081-5/fulltext
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