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Glixx Laboratorie
CAS: 1599440-13-7
Chemical Name: 6-(2,5-Dioxopyrrol-1-yl)-N-[2-[[2-[[(2S)-1-[[2-[[2-[[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]amino]-2-oxoethoxy]methylamino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]hexanamide
Purity: >98% (HPLC)
Novel covalent DNA topoisomerase I inhibitor for conjugating with antibody Trastuzumab to form an anti-tumor HER2-targeting antibody-drug conjugate
References:
https://pubmed.ncbi.nlm.nih.gov/?term=Deruxtecan&sort=date
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