Glixx Laboratories Inc

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Glixx Laboratorie

 

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 NGI-1

 

CAS: 790702-57-7

 

Chemical Name: ML414; 5-(dimethylsulfamoyl)-N-(5-methyl-1,3-thiazol-2-yl)-2-(pyrrolidin-1-yl)benzamide

 

 

GLXC-09454        Cat No: GLXC-09454

 

 

Purity:               > 98% (HPLC)

Storage:             Refrigerator (4 °C)

 


Product Description:

Novel cell-permeable inhibitor of oligosaccharyltransferase (OST), blocking cell-surface localization and signaling of the epidermal growth factor receptor (EGFR) glycoprotein in non-small-cell lung cancer cells, but selectively arresting proliferation in only those cell lines that are dependent on EGFR (or fibroblast growth factor, FGFR) for survival

 

References:

1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854512/

2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393272/

 

Analytical data click for PDF file

 

 

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