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CAS: N/A
Chemical Name: (R)-N-(1-Acryloylpyrrolidin-3-yl)-5-(*S)-(2-methyl-4-phenoxyphenyl)-4-oxo4,5-dihydro-3H-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide.
Purity: >98% (HPLC)
Novel potent and selective covalent inhibitor of Bruton’s tyrosine kinase (BTK), targeting a noncatalytic cysteine residue (Cys481) for covalent bond formation
Ref: https://pubs.acs.org/doi/10.1021/acsmedchemlett.1c00044
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