Glixx Laboratories Inc

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 PF-06700841 Hydrochloride

 

CAS: 1883299-62-4 (free base)

 

Chemical Name: [(1S)-2,2-Difluorocyclopropyl][3-[2-[(1-methyl-1H-pyrazol-4-yl)amino]-4-pyrimidinyl]-3,8-diazabicyclo[3.2.1]oct-8-yl]-methanone tosylat

 

 

GLXC-11360        Cat No: GLXC-11360

 

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 


Product Description:

Novel inhibitor of JAK1 and TYK2 kinases, preventing IL-23 (interleukin 23) signaling through TYK2 (Tyrosine-protein kinase 2)/JAK1 (Janus kinase 1) inhibition

 

References:

1) https://www.jidonline.org/article/S0022-202X(20)31379-8/fulltext

2) https://www.jidonline.org/article/S0022-202X(20)30027-0/fulltext

3) https://pubs.acs.org/doi/10.1021/acs.jmedchem.8b00917

 

Analytical data click for PDF file

 

 

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