Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2523016-96-6
Chemical Name: N-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-12-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamide
Purity: >90% (HPLC)
Highly potent and efficacious proteolysis targeting chimera (PROTAC) degrader of PARP1 for treating cancers, potently inhibiting the growth of cancer cells bearing BRCA1/2 mutations and inducing potent and specific degradation of PARP1 in various human cancer cells even at low picomolar concentrations
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00821
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