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Glixx Laboratorie
CAS: N/A
Chemical Name: (Z)-2-((6-((2,4-Dioxothiazolidin-5-ylidene)methyl)naphthalen-2-yl)oxy)-N-(p-tolyl)acetamide
Purity: >98% (HPLC)
Novel anticancer agent, targeting PPARγ and HDAC4, being cytotoxic to CCRF-CEM cells (CC50 = 2.8 μM), inducing apoptosis, and causing DNA fragmentation, modulating the expression of c-Myc, cleaving caspase-3, and causing in vivo tumor regression in CCRF-CEM tumor xenografts
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00491
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