Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2097117-06-9
Chemical Name: AF27139 ; (S)-N-(2-(4-Chlorophenyl)-2-morpholinoethyl)-2-(pyrimidin-2-yl)-4-(trifluoromethyl)thiazole-5-carboxamide
Purity: >98% (HPLC)
Novel rodent-active and CNS-penetrant P2X7 receptor antagonist, inhibiting LPS stimulated and BzATP-induced IL-1β production
References:
1) https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c02249
2) https://link.springer.com/article/10.1007/s11302-016-9522-7
3) https://www.sciencedirect.com/science/article/pii/S0925443918300139
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