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CAS: N/A
Chemical Name: Ethyl (R)-4-fluoro-1-(1-phenylethyl)-1H-imidazole-5-carboxylate
Purity: >98% (HPLC)
Novel etomidate analogue, enhancing GABAA receptors currents with a concentration for 50% of maximal effect (EC50) of 0.98 {plus minus} 0.02 μM, which was about three times more potent than etomidate (3.07 {plus minus} 1.67 μM), retaining the favorable properties of etomidate, including potent hypnotic effect, rapid onset and recovery, stable hemodynamics and high therapeutic index without suppression of adrenocortical function
Ref: https://jpet.aspetjournals.org/content/early/2021/09/14/jpet.121.000691
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