Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 175013-84-0
Chemical Name: SB-220453; N-[(3S,4S)-6-Acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-3-chloro-4-fluorobenzamide
Purity: >98% (HPLC)
Inhibitor of gap-junction-mediated processes including cortical spreading depression and trigeminal ganglion neuronal-satellite cell signaling, binding to a unique stereoselective binding site in astrocytes, preventing inflammatory damage in the central nervous system by blocking connexin43 hemichannels
References:
1) https://www.nature.com/articles/nature18268
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722754/
3) https://www.painphysicianjournal.com/current/pdf?article=MjAzNA%3D%3D&journal=80
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