Glixx Laboratories Inc

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Glixx Laboratorie

 

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 ARV-825

 

CAS: 1818885-28-7

 

Chemical Name: OTX015-Pomalidomide conjugate; 2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)ethoxy)-phenyl)acetamide

 

 

GLXC-09622        Cat No: GLXC-09622

 

 

Purity:               > 98% (HPLC)

Storage:             Refrigerator (4 °C)

 


Product Description:

Novel PROTAC consisting of OTX015 (a classic BRD4 binding moiety) and pomalidomide (a third-generation immunomodulatory drug binding to the E3 ubiquitin ligase)

 

References:

1) https://www.nature.com/articles/s41598-020-59966-5

2) https://www.sciencedirect.com/science/article/pii/S1074552115001933?via%3Dihub

 

Analytical data click for PDF file

 

 

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